Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22480217 | 0.95 | TAAR1 (0.50) | TAAR1IDO1HRH3DAOCYP4F2 | |
| SCHEMBL10204846 | 0.89 | TAAR1 (0.55) | TAAR1IDO1HRH3KCNH2DAO | |
| SCHEMBL14234021 | 0.84 | CYP4F2 (0.43) | IDO1KCNH2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL15432887 | 0.83 | TAAR1 (0.49) | TAAR1IDO1HRH3KCNH2DAO | |
| SCHEMBL12136331 | 0.81 | TAAR1 (0.55) | TAAR1IDO1HRH3DAOALDH1A1 | |
| SCHEMBL20463165 | 0.81 | SMN1; SMN2 (0.40) | TAAR1IDO1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL8092500 | 0.80 | TAAR1 (0.68) | TAAR1IDO1HRH3DAOGPR84 | |
| SCHEMBL8099771 | 0.80 | TAAR1 (0.68) | TAAR1IDO1HRH3DAOGPR84 | |
| SCHEMBL14228549 | 0.80 | IDO1 (0.56) | TAAR1IDO1ALDH1A1CYP2D6 | |
| SCHEMBL167733 | 0.79 | TAAR1 (0.61) | TAAR1IDO1HRH3DAORAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079918-B2 | Macrocycles as factor XIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-07-14 | — | — | US | disclosed |
| US-20140343276-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343276-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | TAAR1 4566/4885IDO1 2082/4885HRH3 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.