Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.36 |
| ▸ | MDH2 | P40926 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730689 | 0.90 | KDM4E (0.47) | KIF11PARP1MAPKAPK2MAPTMEN1 | |
| SCHEMBL14730855 | 0.88 | MAPKAPK2 (0.49) | MAPKAPK2MEN1KMT2AGSK3BCCNB2 | |
| SCHEMBL14730846 | 0.86 | KDM4E (0.51) | KIF11PARP1MAPKAPK2MAPK1MEN1 | |
| SCHEMBL14730732 | 0.81 | KDM4E (0.43) | MAPKAPK2MAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL14730800 | 0.81 | PARP1 (0.49) | PARP1MAPKAPK2MAPTALDH1A1KMT2A | |
| SCHEMBL14730798 | 0.81 | RAB9A (0.44) | MAPKAPK2NPC1RAB9AJAK2KDR | |
| SCHEMBL14730729 | 0.80 | KDM4E (0.48) | MAPKAPK2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL14730766 | 0.79 | RAB9A (0.47) | NPC1RAB9AJAK2KDR | |
| SCHEMBL14730768 | 0.79 | RAB9A (0.50) | MAPKAPK2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL14730765 | 0.78 | MAPKAPK2 (0.35) | MAPKAPK2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340539-B2 | Hepatitis C inhibitor compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-05-17 | — | — | US | disclosed |
| US-20140343077-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343077-A1 | HEPATITIS C INHIBITOR COMPOUNDS | HCCS, C1R, HAVCR2 | KIF11 3907/4885PARP1 3610/4885MAPKAPK2 4574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.