Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 19/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991726 | 0.94 | FABP4 (0.68) | FABP4HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL21966582 | 0.94 | FABP4 (0.68) | FABP4HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL6987893 | 0.89 | FABP4 (0.60) | FABP4HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL6985500 | 0.87 | HCRTR1 (0.54) | FABP4HCRTR1HCRTR2 | |
| SCHEMBL6988483 | 0.86 | FABP4 (0.58) | FABP4HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL6990510 | 0.85 | HCRTR1 (0.56) | FABP4HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL6991393 | 0.85 | FABP4 (0.61) | FABP4HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL3700092 | 0.84 | FABP4 (0.67) | FABP4HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL3700088 | 0.84 | FABP4 (0.67) | FABP4HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL6989874 | 0.84 | FABP4 (0.54) | FABP4HCRTR1HCRTR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889683-B2 | Substituted quinoxalines as inhibitors of fatty acid binding protein | MERCK SHARP & DOHME CORP. (US) | 2014-11-18 | — | — | US | disclosed |