Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | BID | P55957 | 5/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 4/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.42 |
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692222 | 0.81 | CA12 (0.55) | PPARACA12CA1CA2CA7 | |
| SCHEMBL22408017 | 0.75 | PPARA (0.78) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL2129140 | 0.70 | BID (0.76) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL19605716 | 0.70 | CA12 (0.67) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL67967 | 0.69 | CA12 (0.53) | PPARACA12CA1CA2CA7 | |
| SCHEMBL5997927 | 0.69 | CA12 (0.46) | PPARACA12CA1CA2CA7 | |
| SCHEMBL23162279 | 0.69 | TAAR1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14612075 | 0.68 | PPARA (0.49) | PPARACA12CA1CA2CA7 | |
| SCHEMBL5551371 | 0.68 | PPARA (0.69) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL1033295 | 0.68 | TSHR (0.50) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421903-B1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2014-11-19 | — | — | EP | disclosed |