SCHEMBL2129140

SCHEMBL2129140

CCCc1cccc(O)c1C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 7/20 0.76
MCL1 Q07820 7/20 0.76
BCL2L1 Q07817 6/20 0.76
BAK1 Q16611 6/20 0.76
KAT8 Q9H7Z6 3/20 0.76
EP300 Q09472 2/20 0.76
KAT5 Q92993 2/20 0.76
SAE1 Q9UBE0 2/20 0.76
PPARG P37231 1/20 0.76
PPARA Q07869 1/20 0.76
KAT2A Q92830 1/20 0.76
KAT2B Q92831 1/20 0.76
F7 P08709 3/20 0.64
F3 P13726 3/20 0.64
MMP2 P08253 2/20 0.64
KDM4E B2RXH2 1/20 0.64
MAPT P10636 1/20 0.64
ALOX15 P16050 1/20 0.64
ECE1 P42892 1/20 0.64
SGMS1 Q86VZ5 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL10784024 0.91 BID (0.64) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL4959472 0.89 BID (0.88) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5162912 0.88 BID (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL300853 0.88 BID (0.97) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL3954149 0.86 BID (0.67) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL29919590 0.86 BID (0.67) BIDMCL1BCL2L1BAK1KAT8
Anacardic Acid SCHEMBL627981 0.86 BID (1.00) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5378991 0.86 BID (1.00) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL10877233 0.86 BID (1.00) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL16237264 0.86 BID (1.00) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1345760-A4 pH DEPENDENT MEMBRANE DIFFUSION PENN STATE RES FOUND (US) 2005-03-09 EP claimed
EP-1345760-A2 pH DEPENDENT MEMBRANE DIFFUSION THE PENN STATE RESEARCH FOUNDATION (US) 2003-09-24 EP claimed
WO-2002036230-A9 pH DEPENDENT MEMBRANE DIFFUSION PENN STATE RES FOUND (US) 2003-08-28 WO claimed
US-6558546-B2 pH dependent membrane diffusion THE PENN STATE RESEARCH FOUNDATION 2003-05-06 US claimed
US-20020088748-A1 pH dependent membrane diffusion PENN STATE RESEARCH FOUNDATION, THE 2002-07-11 US claimed
WO-2002036230-A2 pH DEPENDENT MEMBRANE DIFFUSION THE PENN STATE RESEARCH FOUNDATION (US) 2002-05-10 WO claimed
EP-0443742-B1 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-01 EP claimed
US-5476754-A Presensitized; hydrophilic surface on substrate; light sensitive layer containing alkaline water-soluble photocrosslinkable copolycondensed diazo resin FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US claimed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP claimed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP claimed
EP-0083971-B1 PHOTOSENSITIVE COMPOSITION KONICA CORPORATION (JP) 1987-04-01 EP claimed
US-4536465-A CONTAINING CARBOXY, OXY, AROMATIC COMPOUND AND ALDEHYDE OR KETONE WITH A NOVOLAK RESIN KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-08-20 US claimed
EP-0083971-A2 Photosensitive composition KONICA CORPORATION (JP) 1983-07-20 EP claimed
EP-3800247-A1 BIOTECHNOLOGICAL PRODUCTION OF ALKYLPHENOLS AND THEIR USES Johann Wolfgang Goethe-Universität Frankfurt (DE) 2021-04-07 EP disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1249731-B1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORP (JP) 2012-04-25 EP disclosed
EP-0226266-A2 Use of a tetrahydrocarbazolone derivative for the manufacture of medicaments GLAXO GROUP LIMITED (GB) 1987-06-24 EP disclosed
EP-0083971-B1 PHOTOSENSITIVE COMPOSITION KONICA CORPORATION (JP) 1987-04-01 EP disclosed
US-4536465-A CONTAINING CARBOXY, OXY, AROMATIC COMPOUND AND ALDEHYDE OR KETONE WITH A NOVOLAK RESIN KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-08-20 US disclosed
EP-0083971-A2 Photosensitive composition KONICA CORPORATION (JP) 1983-07-20 EP disclosed