Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 16/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | KDM6A | O15550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21227864 | 0.92 | CTSK (0.50) | CTSKCA1CA2KDM4DCYP2C9 | |
| SCHEMBL12026411 | 0.86 | CTSK (0.59) | CTSKCA1CA2KDM4DCYP2C9 | |
| SCHEMBL14024975 | 0.86 | CTSK (0.59) | CTSKCA1CA2KDM4DCYP2C9 | |
| SCHEMBL21779949 | 0.86 | CTSK (0.59) | CTSKCA1CA2KDM4DCYP2C9 | |
| SCHEMBL21527239 | 0.82 | CTSK (0.56) | CTSKCA1CA2KDM4DCYP2C9 | |
| SCHEMBL16253364 | 0.81 | CA1 (0.39) | CA1CA2KDM4D | |
| SCHEMBL513076 | 0.81 | HRH3 (0.37) | KDM4D | |
| SCHEMBL24261283 | 0.80 | CTSK (0.53) | CTSKCA1CA2KDM4DCYP2C9 | |
| SCHEMBL16407677 | 0.80 | CTSK (0.53) | CTSKCA1CA2KDM4DCYP2C9 | |
| SCHEMBL1456569 | 0.80 | CTSK (0.55) | CTSKCA1CA2KDM4DCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889704-B2 | Triazolopyridine compounds as PIM kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2014-11-18 | — | — | US | disclosed |