Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.57 |
| ▸ | THRA | P10827 | 6/20 | 0.57 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400012 | 0.86 | THRB (0.57) | THRBTHRAALDH5A1ABATKMT2A | |
| SCHEMBL11295866 | 0.81 | THRB (0.59) | THRBTHRAALDH5A1ABATKMT2A | |
| SCHEMBL4464368 | 0.81 | MEN1 (0.61) | THRBTHRAALDH5A1ABATKMT2A | |
| SCHEMBL13227566 | 0.80 | AKT1 (0.46) | THRBTHRAKMT2AMEN1AKT1 | |
| Methane SCHEMBL27575376 | 0.79 | MEN1 (0.59) | THRBTHRAALDH5A1ABATKMT2A | |
| SCHEMBL3435838 | 0.77 | EPHX2 (0.49) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL444583 | 0.77 | MEN1 (0.59) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL27624453 | 0.77 | THRB (0.49) | THRBTHRAALDH5A1ABATKMT2A | |
| SCHEMBL11508489 | 0.76 | THRB (0.57) | THRBNPC1RAB9APOLBCYP2C9 | |
| SCHEMBL25468057 | 0.76 | NPC1 (0.41) | THRBTHRAKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731571-B1 | SOLUBILIZER AND COMPOSITION CONTAINING SAME | KUREHA CORP (JP) | 2014-11-19 | — | — | EP | disclosed |