SCHEMBL16256339

SCHEMBL16256339

Nc1ccccc1OCS

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
APP P05067 1/20 0.50
LMNA P02545 1/20 0.48
RECQL P46063 1/20 0.48
KDM4E B2RXH2 2/20 0.43
MAPT P10636 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890759 0.82 KDM4E (0.46) ALDH1A1CYP1A2TDP1APPLMNA
SCHEMBL29367596 0.82 KDM4E (0.46) ALDH1A1CYP1A2TDP1APPLMNA
SCHEMBL23222069 0.80 CYP1A2 (0.66) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2B
SCHEMBL29708563 0.80 CYP1A2 (0.72) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2B
SCHEMBL8569016 0.80 ALDH1A1 (0.67) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2B
SCHEMBL864648 0.80 CYP1A2 (0.72) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2B
Benzene SCHEMBL22129849 0.79 KDM4E (0.44) ALDH1A1TDP1LMNAKDM4EMAPT
SCHEMBL10386552 0.78 CYP1A2 (0.76) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2B
Hydrochloric Acid SCHEMBL11206646 0.78 ALDH1A1 (0.64) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2B
SCHEMBL10387995 0.78 CYP1A2 (0.76) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302010-B1 Ink composition and method of producing a processed product of printed matter FUJIFILM CORP (JP) 2017-09-13 EP disclosed
WO-2014186571-A1 BENZOXAZOLE-BASED MATERIALS FOR VULCANIZATION ACCELERATOR APPLICATIONS THE UNIVERSITY OF AKRON (US) 2014-11-20 WO disclosed