Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23084299 | 0.90 | KMT2A (0.52) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL16000763 | 0.90 | KMT2A (0.52) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL25950660 | 0.90 | KMT2A (0.52) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL5967446 | 0.89 | MDM4 (0.59) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL31276348 | 0.89 | MDM4 (0.59) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL29455664 | 0.89 | MDM4 (0.59) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL119637 | 0.89 | MDM4 (0.59) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL119688 | 0.89 | MDM4 (0.59) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL29528770 | 0.89 | MDM4 (0.59) | KMT2ACASP3MDM4TP53TLR2 | |
| SCHEMBL10028351 | 0.88 | KMT2A (0.53) | KMT2ACASP3MDM4TP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889843-B2 | Nucleic acid synthesizing dimer amidite and nucleic acid synthesizing method | APTA BIOSCIENCES LTD. (GB) | 2014-11-18 | — | — | US | disclosed |