SCHEMBL16257992

SCHEMBL16257992

CCCCCC1CCC(C2CCC(C(F)(F)Oc3ccc(OC(F)(F)F)c(F)c3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
MCHR1 Q99705 1/20 0.34
EPHX2 P34913 8/20 0.33
PDE2A O00408 3/20 0.32
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31
CHRM2 P08172 2/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12624290 1.00 SLC7A5 (0.35) SLC7A5FFAR4MCHR1EPHX2PDE2A
SCHEMBL16258068 0.97 SLC7A5 (0.36) SLC7A5FFAR4MCHR1EPHX2PDE2A
SCHEMBL18032128 0.94 SLC7A5 (0.32) SLC7A5FFAR4MCHR1EPHX2
SCHEMBL12622880 0.94 SLC7A5 (0.32) SLC7A5FFAR4MCHR1EPHX2PDE2A
SCHEMBL12622772 0.94 SLC7A5 (0.32) SLC7A5FFAR4MCHR1EPHX2PDE2A
SCHEMBL12621685 0.92 ALOX5AP (0.36) SLC7A5FFAR4MCHR1EPHX2
SCHEMBL16258082 0.92 FFAR4 (0.36) SLC7A5FFAR4MCHR1EPHX2PDE2A
SCHEMBL12621691 0.92 CTSK (0.35) SLC7A5FFAR4MCHR1EPHX2CHRM2
SCHEMBL12621687 0.90 CTSK (0.32) SLC7A5MCHR1EPHX2
SCHEMBL18032366 0.90 SLC7A5 (0.33) SLC7A5MCHR1EPHX2PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 US disclosed
US-9650572-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-05-16 US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 US disclosed
US-9518221-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2016-12-13 US disclosed
US-9487705-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2016-11-08 US disclosed
US-9464230-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2016-10-11 US disclosed
US-9441160-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2016-09-13 US disclosed
US-20150307780-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2015-10-29 US disclosed
US-20150291881-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-10-15 US disclosed
US-20150252262-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2015-09-10 US disclosed
US-20150225648-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-08-13 US disclosed
EP-2883938-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DIC Corporation (JP) 2015-06-17 EP disclosed
US-20150159089-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2015-06-11 US disclosed
US-20150108403-A1 Liquid crystal composition and liquid crystal display element DIC CORPORATION (JP) 2015-04-23 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed
EP-2806011-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2014-11-26 EP disclosed