SCHEMBL16258013

SCHEMBL16258013

CCc1ccc(-c2ccc(-c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.37
CYP17A1 P05093 3/20 0.37
CYP11B1 P15538 2/20 0.37
CYP11B2 P19099 2/20 0.37
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
KIF11 P52732 1/20 0.36
ALOX5AP P20292 2/20 0.35
FEN1 P39748 2/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CHKA P35790 1/20 0.35
TAAR1 Q96RJ0 2/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP19A1 P11511 1/20 0.34
FAAH O00519 1/20 0.34
GCGR P47871 1/20 0.34
MAPK14 Q16539 1/20 0.34
AKR1C3 P42330 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13083533 0.98 RARB (0.38) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL30201459 0.98 RARB (0.38) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL12850413 0.98 RARB (0.38) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL16257978 0.92 RARB (0.35) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL19007867 0.89 RARB (0.43) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL13253648 0.89 RARB (0.43) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL16257976 0.88 CYP17A1 (0.49) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL16258016 0.88 CYP17A1 (0.49) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL16258035 0.88 CYP17A1 (0.49) RARBCYP17A1CYP11B1CYP11B2RARA
SCHEMBL16258069 0.87 LMNA (0.39) RARBKIF11ALOX5APFEN1CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160024383-A1 LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2016-01-28 US disclosed
US-20160024383-A1 LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2016-01-28 US disclosed
EP-2806011-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2014-11-26 EP disclosed