Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258062 | 1.00 | NFE2L2 (0.46) | NFE2L2PTGS2AKR1C3AKR1C2PDE3B | |
| SCHEMBL16258090 | 1.00 | NFE2L2 (0.46) | NFE2L2PTGS2AKR1C3AKR1C2PDE3B | |
| SCHEMBL4567629 | 0.92 | PDE3B (0.48) | PTGS2AKR1C3AKR1C2PDE3BPDE3A | |
| SCHEMBL16748050 | 0.90 | NFE2L2 (0.44) | NFE2L2PTGS2AKR1C3AKR1C2PDE3B | |
| SCHEMBL12889477 | 0.90 | NFE2L2 (0.47) | NFE2L2PTGS2AKR1C3AKR1C2PDE3B | |
| SCHEMBL12826296 | 0.90 | NFE2L2 (0.47) | NFE2L2PTGS2AKR1C3AKR1C2PDE3B | |
| SCHEMBL170435 | 0.90 | PDE3B (0.49) | PTGS2AKR1C3AKR1C2PDE3BPDE3A | |
| SCHEMBL12011026 | 0.89 | NFE2L2 (0.54) | NFE2L2PTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL265481 | 0.89 | NFE2L2 (0.54) | NFE2L2PTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL16258105 | 0.89 | NFE2L2 (0.54) | NFE2L2PTGS2AKR1C3AKR1C2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024383-A1 | LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME | DIC CORPORATION (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-2806011-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DIC Corporation (JP) | 2014-11-26 | — | — | EP | disclosed |