Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45820 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL29354355 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL24942524 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL23171858 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL16543342 | 0.95 | ALDH1A1 (0.55) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL18946156 | 0.93 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL24383308 | 0.93 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL1108317 | 0.93 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL13344789 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL7977387 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TP53TSHRHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609136-B1 | FORMULATED BENZOXAZINE BASED SYSTEM FOR TRANSPORTATION APPLICATIONS | HUNTSMAN ADV MAT AMERICAS INC (US) | 2014-11-26 | — | — | EP | disclosed |