Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664476 | 0.90 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19LMNAGAA | |
| SCHEMBL662306 | 0.89 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19LMNAGAA | |
| SCHEMBL661677 | 0.89 | LMNA (0.42) | CYP1A2CYP2C9CYP2C19LMNAGAA | |
| SCHEMBL662235 | 0.88 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19LMNAGAA | |
| SCHEMBL663819 | 0.87 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19LMNAGAA | |
| SCHEMBL661616 | 0.87 | LMNA (0.42) | CYP1A2CYP2C9CYP2C19LMNAGAA | |
| SCHEMBL14713970 | 0.85 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19LMNAGAA | |
| SCHEMBL16258377 | 0.78 | CETP (0.49) | LMNAGAAHTTCETP | |
| SCHEMBL661613 | 0.78 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19LMNAGAA | |
| SCHEMBL662261 | 0.76 | LMNA (0.44) | CYP1A2CYP2C9CYP2C19LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536733-B1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INT (DE) | 2014-11-26 | — | — | EP | disclosed |