Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850399 | 0.93 | ALDH1A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL14842871 | 0.93 | ALDH1A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL14850400 | 0.89 | ITGB1 (0.33) | MAPT | |
| SCHEMBL20077203 | 0.79 | MAPT (0.33) | ALDH1A1MAPT | |
| SCHEMBL20077396 | 0.78 | CYP1A2 (0.37) | ALDH1A1MAPT | |
| SCHEMBL16260004 | 0.76 | MAPT (0.34) | ALDH1A1MAPT | |
| SCHEMBL21955687 | 0.75 | CYP1A2 (0.47) | ALDH1A1MAPT | |
| SCHEMBL14850396 | 0.75 | MAPT (0.33) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL16243348 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL16243347 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9468625-B2 | Organonitro thioether compounds and medical uses thereof | EPICENTRX, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-20160081981-A1 | ORGANONITRO THIOETHER COMPOUNDS AND MEDICAL USES THEREOF | RADIORX, INC. | 2016-03-24 | — | — | US | disclosed |
| US-9139519-B2 | Organonitro thioether compounds and medical uses thereof | EPICENTRX, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20140349988-A1 | ORGANONITRO THIOETHER COMPOUNDS AND MEDICAL USES THEREOF | RADIORX, INC. (US) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349988-A1 | ORGANONITRO THIOETHER COMPOUNDS AND MEDICAL USES THEREOF | SLC22A8, SLCO2A1, SLCO2B1 | ALDH1A1 1453/4885MAPT 2777/4885 |
| US-20160081981-A1 | ORGANONITRO THIOETHER COMPOUNDS AND MEDICAL USES THEREOF | SLC22A8, XPOT, NPM1 | ALDH1A1 2447/4885MAPT 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.