SCHEMBL16259100

SCHEMBL16259100

CCOC(=O)c1ccc2cc(C(=O)OC)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.59
CA1 P00915 4/20 0.59
CA2 P00918 4/20 0.59
CA7 P43166 4/20 0.59
CA9 Q16790 4/20 0.59
CA14 Q9ULX7 4/20 0.59
HSD17B2 P37059 1/20 0.57
PTPN11 Q06124 1/20 0.55
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAOA P21397 1/20 0.53
LCK P06239 1/20 0.53
RAB9A P51151 2/20 0.51
MEN1 O00255 1/20 0.51
THRB P10828 1/20 0.51
KMT2A Q03164 1/20 0.51
SLC2A1 P11166 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707407 0.93 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL9979785 0.89 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL1960994 0.87 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL4444431 0.87 CA1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL10537396 0.87 CA1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL29365729 0.87 PTPN11 (0.68) CA12CA1CA2CA7CA9
SCHEMBL69025 0.87 PTPN11 (0.68) CA12CA1CA2CA7CA9
SCHEMBL15315290 0.86 KDM4E (0.59) CA12CA1CA2CA7CA9
SCHEMBL9698077 0.86 KDM4E (0.62) CA12CA1CA2CA7CA9
SCHEMBL7642823 0.86 HRH3 (0.61) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180066111-A1 COPOLYESTERIMIDES DERIVED FROM N,N'-BIS-(HYDROXYALKYL)-BENZOPHENONE-3,3',4,4'-TETRACARBOXYLIC DIIMIDE AND FILMS MADE THEREFROM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2018-03-08 US disclosed
US-9840590-B2 Copolyesterimides derived from N,N′-bis-(hydroxyalkyl)-benzophenone-3,3′,4,4′-tetracarboxylic diimide and films made therefrom DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2017-12-12 US disclosed
US-20170174831-A1 COPOLYESTERIMIDES COMPRISING BIS(2-HYDROXYALKYL)-2,2'-(1,4-PHENYLENE)BIS(1,3-DIOXOISOINDOLINE-5-CARBOXYLATE) AND ARTICLES MADE THEREFROM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2017-06-22 US disclosed
US-9637588-B2 Copolyesterimides derived from aromatic dicarboxylic acids and aliphatic glycols and films made therefrom DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2017-05-02 US disclosed
US-20160251476-A1 COPOLYESTERIMIDES DERIVED FROM AROMATIC DICARBOXYLIC ACIDS AND ALIPHATIC GLYCOLS AND FILMS MADE THEREFROM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2016-09-01 US disclosed
US-9422399-B2 Copolyesterimides derived from N,N′-bis-(hydroxyalkyl)-3,3′,4,4′-diphenylsulfonetetracarboxylic diimide and films made therefrom DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2016-08-23 US disclosed
US-20160137790-A1 COPOLYESTERIMIDES DERIVED FROM N,N'-BIS-(HYDROXYALKYL)-BENZOPHENONE-3,3',4,4'-TETRACARBOXYLIC DIIMIDE AND FILMS MADE THEREFROM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2016-05-19 US disclosed
US-20160130399-A1 COPOLYESTERIMIDES DERIVED FROM N,N'-BIS-(HYDROXYALKYL)-3,3',4,4'-DIPHENYLSULFONETETRACARBOXYLIC DIIMIDE AND FILMS MADE THEREFROM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2016-05-12 US disclosed
US-20160122475-A1 COPOLYESTERIMIDES DERIVED FROM N,N'-BIS-(HYDROXYALKYL)-PYROMELLITIC DIIMIDE AND FILMS MADE THEREFROM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2016-05-05 US disclosed
US-9096724-B2 Copolyesterimides of poly(alkylene naphthalate)s having high glass transition temperature and film made therefrom DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2015-08-04 US disclosed
US-20140350210-A1 COPOLYESTERIMIDES OF POLY(ALKYLENE NAPHTHALATE)S HAVING HIGH GLASS TRANSITION TEMPERATURE AND FILM MADE THEREFROM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP 2014-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174831-A1 COPOLYESTERIMIDES COMPRISING BIS(2-HYDROXYALKYL)-2,2'-(1,4-PHENYLENE)BIS(1,3-DIOXOISOINDOLINE-5-CARBOXYLATE) AND ARTICLES MADE THEREFROM PUF60, PDS5A, DDT CA12 1511/4885CA1 1896/4885CA2 1965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.