SCHEMBL16259459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL827333	0.96	TSHR (0.50)	TSHRCYP3A4SLC22A2SLC22A1SLC22A3
	SCHEMBL2117825	0.91	CYP3A4 (0.54)	TSHRCYP3A4SLC22A2SLC22A1SLC22A3
	SCHEMBL5116040	0.90	TSHR (0.45)	TSHRCYP3A4SLC22A2SLC22A1SLC22A3
	SCHEMBL28772905	0.83	CYP3A4 (0.47)	TSHRCYP3A4TRPA1MAPK1TDP1
	SCHEMBL28473582	0.83	CYP3A4 (0.47)	TSHRCYP3A4TRPA1MAPK1TDP1
	SCHEMBL3177458	0.83	CYP3A4 (0.50)	TSHRCYP3A4SLC22A2SLC22A1SLC22A3
	SCHEMBL22966351	0.83	CYP3A4 (0.50)	TSHRCYP3A4SLC22A2SLC22A1SLC22A3
	SCHEMBL305480	0.83	CYP3A4 (0.50)	TSHRCYP3A4SLC22A2SLC22A1SLC22A3
	SCHEMBL305469	0.83	CYP3A4 (0.50)	TSHRCYP3A4SLC22A2SLC22A1SLC22A3
	SCHEMBL22966434	0.78	CYP3A4 (0.45)	TSHRCYP3A4SLC22A2SLC22A1SLC22A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.