Sugi Predict

Sugi Predict / Targets / SGTA

SGTA

Small glutamine-rich tetratricopeptide repeat-containing protein alpha · O43765 · SGTA on Sugi Atlas →

272 patent compounds predicted against SGTA, 228 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL8288590 SCHEMBL8288590 0.76 1/20
SCHEMBL7003055 SCHEMBL7003055 0.74 1/20
SCHEMBL5451446 SCHEMBL5451446 0.71 1/20
SCHEMBL5453282 SCHEMBL5453282 0.71 1/20
SCHEMBL7002920 SCHEMBL7002920 0.70 1/20
SCHEMBL5460515 SCHEMBL5460515 0.69 1/20
SCHEMBL8289514 SCHEMBL8289514 0.69 1/20
SCHEMBL13574989 SCHEMBL13574989 0.69 1/20
SCHEMBL8288668 SCHEMBL8288668 0.68 1/20
SCHEMBL8289505 SCHEMBL8289505 0.68 1/20
SCHEMBL11324603 SCHEMBL11324603 0.66 1/20
SCHEMBL26293177 SCHEMBL26293177 0.64 1/20
SCHEMBL5449182 SCHEMBL5449182 0.63 1/20
SCHEMBL26294993 SCHEMBL26294993 0.63 1/20
SCHEMBL1067537 SCHEMBL1067537 0.62 1/20
SCHEMBL8289822 SCHEMBL8289822 0.62 1/20
SCHEMBL7003174 SCHEMBL7003174 0.62 1/20
SCHEMBL8277600 SCHEMBL8277600 0.62 1/20
SCHEMBL1066142 SCHEMBL1066142 0.62 1/20
SCHEMBL23657531 SCHEMBL23657531 0.62 1/20

Clinical trials — most relevant to SGTA by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Acute Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon PHASE4COMPLETED
A Phase I Study of Systemic Gene Therapy With SGT-94 in Patients With Solid Tumors PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
PATH Trial: Personalized Approaches in the Treatment of Head and Neck Cancer nanNOT_YET_RECRUITING
Genetic Polymorphism of the Androgen Receptor-Gene and Sexual Function in Middle Aged Women nanCOMPLETED
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients nanUNKNOWN
Genetics of Familial Testicular Cancer nanCOMPLETED
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm nanCOMPLETED
Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
New Genes in the Carcinogenesis of Colorectal Cancer nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
PCM1-JAK2 in Therapy Related Neoplasms nanUNKNOWN
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism nanUNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
Epidemiology of Atherosclerosis nanCOMPLETED
Study of Prostate Cancer in Black and White U.S. Veterans nanCOMPLETED
Biology-Driven Cognitive Profiling in Huntington's Disease nanACTIVE_NOT_RECRUITING
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Cause of Familial Testicular Cancer nanCOMPLETED
Role of Nitric Oxide in Diabetic Patients With Erectile Dysfunction nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
Gene First Approach to Connective Tissue Disease nanCOMPLETED
Study of Skeletal Disorders and Short Stature nanCOMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas nanRECRUITING
Genetics of Rheumatoid Arthritis nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SGTA binder may also engage these)

ProteinNameSimilarity
Q32LM2 — 1.000 Q32LM2 →
O70593 — 0.986 O70593 →
Q96EQ0 — 0.982 Q96EQ0 →
Q8BJU0 — 0.980 Q8BJU0 →
Q80W98 — 0.977 Q80W98 →
Q8VD33 — 0.976 Q8VD33 →
Q99L47 — 0.956 Q99L47 →
Q5ZLF0 — 0.956 Q5ZLF0 →
P50502 — 0.955 P50502 →
P50503 — 0.954 P50503 →
Q5RF31 — 0.951 Q5RF31 →
Q8NFI4 — 0.950 Q8NFI4 →
Q9Y3C0 — 0.947 Q9Y3C0 →
Q9CZW5 — 0.946 Q9CZW5 →
Q5SRX1 — 0.943 Q5SRX1 →
Q05B58 — 0.943 Q05B58 →
Q9DAF3 — 0.943 Q9DAF3 →
Q98SH3 — 0.943 Q98SH3 →
Q75Q39 — 0.942 Q75Q39 →
Q95JI3 — 0.941 Q95JI3 →
A0JPP7 — 0.940 A0JPP7 →
A1L5A6 — 0.940 A1L5A6 →
A4QNE0 — 0.940 A4QNE0 →
PARN Poly(A)-specific ribonuclease PARN 0.940 landscape →
Q5RC51 — 0.939 Q5RC51 →
Q3TDN2 — 0.939 Q3TDN2 →
Q9ERG2 — 0.939 Q9ERG2 →
Q8R1T1 — 0.938 Q8R1T1 →
Q9D1H7 — 0.938 Q9D1H7 →
Q2KIK0 — 0.938 Q2KIK0 →