Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042297 | 0.81 | EPHX2 (0.49) | SLC6A4CYP1A2CYP2D6CYP2C19SLC6A2 | |
| SCHEMBL3289204 | 0.78 | DPP4 (0.49) | SLC6A4CYP2D6SLC6A2SLC6A3EPHX2 | |
| SCHEMBL10716724 | 0.78 | DPP4 (0.49) | SLC6A4CYP2D6SLC6A2SLC6A3EPHX2 | |
| SCHEMBL5203360 | 0.76 | HRH3 (0.62) | — | |
| SCHEMBL3285405 | 0.75 | EPHX1 (0.50) | SLC6A4CYP2D6SLC6A2SLC6A3DPP4 | |
| SCHEMBL8228429 | 0.75 | SLC6A4 (0.56) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL3129564 | 0.74 | SLC6A4 (0.54) | SLC6A4CYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL8039062 | 0.74 | HTT (0.58) | SLC6A4CYP1A2CYP2D6CYP2C19SLC6A2 | |
| SCHEMBL656814 | 0.73 | SLC6A4 (0.73) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL7528408 | 0.73 | SLC6A4 (0.73) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140349297-A1 | FLUORESCENT DYES BASED ON ACRIDINE AND ACRIDINIUM DERIVATIVES | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |