Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040937 | 0.81 | MEN1 (0.39) | HTTCYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL8042890 | 0.81 | HRH3 (0.45) | HTTCYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL8046330 | 0.80 | SCN9A (0.46) | HTTEPHX2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL8464214 | 0.78 | EPHX1 (0.47) | CYP2D6CYP2C19CYP3A4CYP2C9HRH3 | |
| SCHEMBL8040010 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2SLC6A4NPC1RAB9ATAAR1 | |
| SCHEMBL28898677 | 0.78 | EPHX1 (0.36) | HTTCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL11038274 | 0.78 | EPHX1 (0.55) | CYP2D6CYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL934587 | 0.78 | HTT (0.49) | HTTEPHX2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11401428 | 0.75 | HTT (0.49) | HTTCYP2D6CYP2C19HRH3SMN1; SMN2 | |
| SCHEMBL12453120 | 0.75 | EPHX1 (0.50) | CYP2D6CYP2C19CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0675187-B1 | Liquid crystalline compounds and liquid crystal composition | CHISSO CORP (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5670085-A | Liquid crystalline compound and liquid crystal | CHISSO CORPORATION (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5534187-A | CONTAINING CYCLOHEXANE RING | CHISSO CORPORATION (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0675187-A2 | Liquid crystalline compounds and liquid crystal composition | Chisso Corporation (JP) | 1995-10-04 | — | — | EP | disclosed |