Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15855103 | 1.00 | F10 (0.89) | F10KLKB1 | |
| SCHEMBL15855123 | 1.00 | F10 (0.89) | F10KLKB1 | |
| SCHEMBL15855156 | 0.94 | F10 (1.00) | F10KLKB1 | |
| SCHEMBL15855117 | 0.94 | F10 (1.00) | F10KLKB1 | |
| SCHEMBL15856101 | 0.94 | F10 (1.00) | F10KLKB1 | |
| SCHEMBL15855120 | 0.92 | F10 (0.74) | F10KLKB1 | |
| SCHEMBL15855152 | 0.89 | F10 (0.78) | F10KLKB1 | |
| SCHEMBL19527197 | 0.89 | F10 (0.78) | F10KLKB1 | |
| SCHEMBL15855157 | 0.83 | F10 (0.74) | F10 | |
| SCHEMBL19957986 | 0.82 | F10 (0.77) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644195-B2 | Compounds and methods for purification of serine proteases | PORTOLA PHARMACEUTICALS, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-20150337285-A1 | COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES | ALEXION PHARMA INTERNATIONAL OPERATIONS UNLIMITED COMPANY (IE) | 2015-11-26 | — | — | US | disclosed |
| US-20140346397-A1 | COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES | ALEXION PHARMA INTERNATIONAL OPERATIONS UNLIMITED COMPANY (IE) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150337285-A1 | COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES | PRSS1, HPN, PRSS8 | F10 832/4885KLKB1 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.