SCHEMBL16260433

SCHEMBL16260433

c1ccc(-c2cc(-c3ccccc3)nc(-n3c4ccccc4c4cc(-c5ccc(-n6c7ccccc7c7c6ccc6c8ccccc8n(-c8ccccc8)c67)cc5)ccc43)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.38
KDM4E B2RXH2 3/20 0.38
ATM Q13315 1/20 0.38
PTGER4 P35408 1/20 0.33
NR3C1 P04150 1/20 0.33
TSPO P30536 1/20 0.32
HDAC4 P56524 1/20 0.32
PTGES O14684 1/20 0.32
MAPT P10636 3/20 0.31
MAPK1 P28482 3/20 0.31
NPSR1 Q6W5P4 2/20 0.31
HTT P42858 1/20 0.31
NPY5R Q15761 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DHODH Q02127 1/20 0.30
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15197829 0.97 L3MBTL1 (0.39) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL21018138 0.95 L3MBTL1 (0.38) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL17248251 0.94 L3MBTL1 (0.40) L3MBTL1KDM4EATMPTGER4MAPT
SCHEMBL15625697 0.94 L3MBTL1 (0.40) L3MBTL1KDM4EATMPTGER4MAPT
SCHEMBL16260425 0.94 L3MBTL1 (0.40) L3MBTL1KDM4EATMPTGER4MAPT
SCHEMBL17809373 0.94 L3MBTL1 (0.34) L3MBTL1KDM4EATMNR3C1HDAC4
SCHEMBL17248253 0.93 L3MBTL1 (0.41) L3MBTL1KDM4EATMHDAC4MAPT
SCHEMBL19769897 0.93 KDM4E (0.36) L3MBTL1KDM4EATMNR3C1MAPT
SCHEMBL19769865 0.92 L3MBTL1 (0.43) L3MBTL1KDM4EATMPTGER4HDAC4
SCHEMBL19769859 0.92 L3MBTL1 (0.43) L3MBTL1KDM4EATMPTGER4HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140346483-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2014-11-27 US disclosed
US-20140346483-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2014-11-27 US disclosed