SCHEMBL16260482

SCHEMBL16260482

CCOC1=C(C)C(=O)C(OCC)=C(Cl)C1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.35
KDM4E B2RXH2 5/20 0.35
KMT2A Q03164 4/20 0.35
TDP1 Q9NUW8 3/20 0.35
MEN1 O00255 3/20 0.35
PABPC1 P11940 1/20 0.35
PTPRC P08575 1/20 0.34
CDC25B P30305 1/20 0.34
ALDH1A1 P00352 4/20 0.34
HPGD P15428 2/20 0.34
GAA P10253 2/20 0.34
L3MBTL1 Q9Y468 6/20 0.33
NPSR1 Q6W5P4 3/20 0.33
MAPK1 P28482 2/20 0.33
RAB9A P51151 1/20 0.33
ATM Q13315 1/20 0.33
NSD2 O96028 1/20 0.33
HSP90AA1 P07900 1/20 0.33
TSHR P16473 1/20 0.33
CYP1A2 P05177 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12137192 0.89 PTPRC (0.35) MAPTKDM4EKMT2ATDP1MEN1
SCHEMBL7616827 0.85 MAPT (0.43) MAPTKDM4EKMT2ATDP1MEN1
SCHEMBL13478209 0.78 PTPRC (0.30) PTPRCCDC25B
SCHEMBL5589616 0.77 CDC25B (0.41) MAPTKDM4EKMT2ATDP1MEN1
SCHEMBL10446464 0.76 IDO1 (0.56) MAPTKDM4EKMT2ATDP1MEN1
SCHEMBL13417406 0.76 MCOLN3 (0.36) MAPTKDM4EKMT2ATDP1MEN1
Benzene SCHEMBL9714013 0.75 NSD2 (0.58) MAPTKDM4EKMT2ATDP1MEN1
SCHEMBL28765242 0.72 PTPRC (0.51) MAPTKDM4ETDP1PTPRCCDC25B
SCHEMBL9627838 0.71 CDC25B (0.61) MAPTKDM4EKMT2ATDP1MEN1
SCHEMBL10865964 0.71 NSD2 (0.45) MAPTKDM4EKMT2ATDP1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9177997-B2 Memory device SONY CORPORATION (JP) 2015-11-03 US disclosed
US-9177997-B2 Memory device SONY CORPORATION (JP) 2015-11-03 US disclosed
US-20140346430-A1 MEMORY DEVICE SONY CORPORATION (JP) 2014-11-27 US disclosed
US-20140346430-A1 MEMORY DEVICE SONY CORPORATION (JP) 2014-11-27 US disclosed