Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 4/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.58 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.54 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446464 | 0.98 | IDO1 (0.56) | NSD2HSP90AA1HKDC1TLR9IDO1 | |
| SCHEMBL11129631 | 0.87 | MAPT (0.47) | NSD2HSP90AA1HKDC1TLR9IDO1 | |
| SCHEMBL10705446 | 0.86 | PTPN1 (0.55) | NSD2HSP90AA1HKDC1TLR9IDO1 | |
| SCHEMBL10865964 | 0.84 | NSD2 (0.45) | NSD2HSP90AA1HKDC1TLR9IDO1 | |
| SCHEMBL10707493 | 0.84 | PTPN1 (0.61) | NSD2HSP90AA1HKDC1TLR9IDO1 | |
| SCHEMBL3420371 | 0.84 | CDC25B (0.60) | NSD2MAPTTDP1LMNAMAPK1 | |
| SCHEMBL10446166 | 0.80 | IDO1 (0.52) | NSD2HSP90AA1HKDC1TLR9IDO1 | |
| SCHEMBL10737111 | 0.80 | IDO1 (0.52) | NSD2HSP90AA1HKDC1TLR9IDO1 | |
| SCHEMBL12137192 | 0.80 | PTPRC (0.35) | NSD2HSP90AA1MAPTTDP1LMNA | |
| Benzene SCHEMBL9713962 | 0.79 | MAPT (0.69) | NSD2IDO1MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |