SCHEMBL1626076

SCHEMBL1626076

O=C1CCCCCCCCCCCN1Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 1.00
HRH3 Q9Y5N1 2/20 0.69
ACHE P22303 1/20 0.61
GAA P10253 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
DDB1 Q16531 1/20 0.51
CRBN Q96SW2 1/20 0.51
ACACB O00763 1/20 0.50
APP P05067 1/20 0.49
MCHR1 Q99705 1/20 0.49
KCNH2 Q12809 1/20 0.48
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
HSD17B10 Q99714 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610772 1.00 L3MBTL1 (1.00) L3MBTL1HRH3ACHEGAASMN1; SMN2
SCHEMBL7269112 1.00 L3MBTL1 (1.00) L3MBTL1HRH3ACHEGAASMN1; SMN2
SCHEMBL9212361 1.00 L3MBTL1 (1.00) L3MBTL1HRH3ACHEGAASMN1; SMN2
Hydrochloric Acid SCHEMBL12494696 0.98 L3MBTL1 (0.97) L3MBTL1HRH3ACHEGAASMN1; SMN2
SCHEMBL8903528 0.98 L3MBTL1 (0.97) L3MBTL1HRH3ACHEGAASMN1; SMN2
SCHEMBL596252 0.98 L3MBTL1 (0.96) L3MBTL1HRH3ACHEGAASMN1; SMN2
SCHEMBL180739 0.93 L3MBTL1 (0.86) L3MBTL1HRH3ACHEGAASMN1; SMN2
SCHEMBL24938208 0.92 L3MBTL1 (0.84) L3MBTL1HRH3ACHEGAASMN1; SMN2
Hydrochloric Acid SCHEMBL6818365 0.91 L3MBTL1 (0.83) L3MBTL1HRH3ACHEGAASMN1; SMN2
Trifluoroacetic Acid SCHEMBL12493760 0.88 L3MBTL1 (0.78) L3MBTL1HRH3ACHEGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2004744-B1 COMPOSITION INCLUDING MULTIPLE FUNCTIONALIZED POLYMERS BRIDGESTONE CORP (JP) 2017-12-06 EP disclosed
US-9493629-B2 Modified butadiene-based polymer composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-11-15 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-9475924-B2 Rubber composition for tire tread and pneumatic tire using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-10-25 US disclosed
US-20150126643-A1 Rubber Composition for Tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-05-07 US disclosed
US-20130267646-A1 RUBBER COMPOSITION FOR TIRE TREAD AND PNEUMATIC TIRE USING THE SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-10-10 US disclosed
EP-1885775-B1 ENHANCING INTERACTIVITY BETWEEN AMINE-FUNCTIONALIZED POLYMERS AND PARTICULATE FILLERS BRIDGESTONE CORP (JP) 2013-07-24 EP disclosed
EP-1865023-B1 MODIFIED BUTADIENE POLYMER COMPOSITION ASAHI KASEI CHEMICALS CORP (JP) 2011-05-04 EP disclosed
US-7928159-B2 Enhancing interactivity between amine-functionalized polymers and particulate fillers Bridgestone Corpororation (JP) 2011-04-19 US disclosed
US-7767755-B2 Composition including multiple functionalized polymers BRIDGESTONE CORPORATION (JP) 2010-08-03 US disclosed
US-5217839-A Dispersion containing mixture of a polymer with a carbon nitrogen double bond and a colorant in a vinyl monomer NIPPON ZEON CO., LTD. (JP) 1993-06-08 US disclosed
US-5218023-A Anionic polymers NIPPON ZEON CO., LTD. (JP) 1993-06-08 US disclosed
US-5216080-A Butadiene-styrene copolymers endcapped with N-modified amino ketones, thioamino ketones, thioamino aldehydes, lactams, thiolactams, ethyleneurea and thioethylene urea; wear resistant, large-sized tires NIPPON ZEON CO., LTD. (JP) 1993-06-01 US disclosed
US-5155161-A Living polymer modified by lactam, urea, amino ketone or aldehyde or thio analogs, followed by hydrolysis NIPPON ZEON CO., LTD. (JP) 1992-10-13 US disclosed
EP-0488346-A1 Process for preparation of styrene resin composition and styrene resin composition NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0438248-A2 Preparation process of toner NIPPON ZEON CO., LTD. (JP) 1991-07-24 EP disclosed
EP-0435544-A2 Abrasion-resistant rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0434353-A2 Rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0388921-A2 Additive for organic solvent or thermoplastic polymer NIPPON ZEON CO., LTD. (JP) 1990-09-26 EP disclosed
US-4943623-A POLYMERIZED IN AN AMIDE OR LACTAM SOLVENT BAYER AKTIENGESELLSCHAFT (DE) 1990-07-24 US disclosed