Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | SULT1E1 | P49888 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041723 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21742805 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL19844089 | 0.65 | CYP19A1 (0.34) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL12134172 | 0.65 | PTPN1 (0.32) | SMN1; SMN2CYP19A1 | |
| SCHEMBL29371542 | 0.64 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL14879825 | 0.63 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL16414582 | 0.62 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2CYP19A1MEN1KMT2A | |
| SCHEMBL14879992 | 0.61 | SMN1; SMN2 (0.41) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9880769 | 0.61 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL14029401 | 0.61 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150197480-A9 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | ACADEMIA SINICA (TW) | 2015-07-16 | — | — | US | disclosed |
| US-20150197480-A9 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | ACADEMIA SINICA (TW) | 2015-07-16 | — | — | US | disclosed |
| US-20140350100-A1 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | ACADEMIA SINICA (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140350100-A1 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | ACADEMIA SINICA (TW) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350100-A1 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | GLP1R, GIPR, GCGR | ALDH1A1 3934/4885CYP3A4 3791/4885CYP2C9 3522/4885 |
| US-20150197480-A9 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | GLP1R, GIPR, GCGR | ALDH1A1 3934/4885CYP3A4 3791/4885CYP2C9 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.