SCHEMBL1626166

SCHEMBL1626166

CC[n+]1ccccc1Cl.F[B-](F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
STAT3 P40763 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.33
LMNA P02545 2/20 0.31
HPGD P15428 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13215505 0.92
Iodide SCHEMBL5366846 0.90 KDM4E (0.42) KDM4ESMN1; SMN2NPC1RAB9AHTT
Bromide SCHEMBL11484493 0.90 NPC1 (0.41) KDM4ESMN1; SMN2NPC1RAB9AHTT
Benzene SCHEMBL9542509 0.90 KDM4E (0.42) KDM4ESMN1; SMN2NPC1RAB9AHTT
SCHEMBL8505609 0.78 SMN1; SMN2 (0.52) KDM4ESMN1; SMN2NPC1RAB9AHTT
SCHEMBL29475364 0.78 KDM4E (0.37) KDM4ESMN1; SMN2NPC1RAB9AHTT
SCHEMBL1892729 0.78 KDM4E (0.37) KDM4ESMN1; SMN2NPC1RAB9AHTT
SCHEMBL120909 0.76 HDAC8 (0.43) KDM4ESMN1; SMN2NPC1RAB9AHTT
SCHEMBL29387158 0.76 HDAC8 (0.43) KDM4ESMN1; SMN2NPC1RAB9AHTT
SCHEMBL30054627 0.74 HDAC8 (0.42) KDM4ESMN1; SMN2NPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1897901-B1 BIODEGRADABLE POLYMER, PRODUCTION METHOD THEREOF, MOLDED PRODUCT THEREOF, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2015-03-11 EP claimed
US-20090142982-A1 Biodegradable Polymer, Production Method Thereof, Molded Product Thereof, and Use Thereof MITSUI CHEMICALS INC. (JP) 2009-06-04 US claimed
EP-1897901-A1 BIODEGRADABLE POLYMER, PRODUCTION METHOD THEREOF, MOLDED PRODUCT THEREOF, AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2008-03-12 EP claimed
EP-1897901-B1 BIODEGRADABLE POLYMER, PRODUCTION METHOD THEREOF, MOLDED PRODUCT THEREOF, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2015-03-11 EP disclosed
US-7928180-B2 Biodegradable polymer, production method thereof, molded product thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2011-04-19 US disclosed
US-20090142982-A1 Biodegradable Polymer, Production Method Thereof, Molded Product Thereof, and Use Thereof MITSUI CHEMICALS INC. (JP) 2009-06-04 US disclosed
EP-1897901-A1 BIODEGRADABLE POLYMER, PRODUCTION METHOD THEREOF, MOLDED PRODUCT THEREOF, AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2008-03-12 EP disclosed
US-6414003-B1 ANTIULCER AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed
US-6169102-B1 ANTI-HELICOBACTER PYLORI AGENT COMPRISING AN OXAZOLIN-4-ONE DERIVATIVE USEFUL AS A THERAPEUTIC AGENT FOR GASTRIC AND DUODENAL ULCER TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-01-02 US disclosed
EP-0923577-A2 OXAZOLONE DERIVATIVES AND THEIR USE AS ANTI-HELICOBACTER PYLORI AGENT Takeda Chemical Industries, Ltd. (JP) 1999-06-23 EP disclosed
WO-1997049703-A2 OXAZOLONE DERIVATIVES AND THEIR USE AS ANTI-HELICOBACTER PYLORI AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-12-31 WO disclosed
US-5140084-A Heat resistant, high strength adhesives THREE BOND CO., LTD. (JP) 1992-08-18 US disclosed
EP-0459617-A1 Novel silicon containing alpha-cyanoacrylates THREE BOND CO., LTD. (JP) 1991-12-04 EP disclosed
US-4105673-A PROCESS FOR THE PREPARATION OF LACTONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-08-08 US disclosed