Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264009 | 0.88 | MAOB (0.64) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| Deoxysappanone B Trimethyl Ether SCHEMBL4736096 | 0.84 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| Deoxysappanone B Trimethyl Ether SCHEMBL29903817 | 0.84 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28259502 | 0.83 | MAOB (0.72) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16264012 | 0.83 | CYP3A4 (0.60) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8463991 | 0.81 | MAOB (0.65) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17297291 | 0.80 | CYP3A4 (0.83) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8466308 | 0.79 | CYP19A1 (0.63) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4731838 | 0.79 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29903813 | 0.79 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014182695-A1 | COMPOUNDS FOR TREATMENT OF ANGIOGENESIS-MEDIATED DISEASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2014-11-13 | — | — | WO | disclosed |