Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 0.81 |
| ▸ | USP2 | O75604 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | TP53 | P04637 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deoxysappanone B Trimethyl Ether SCHEMBL29903817 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17297291 | 0.91 | CYP3A4 (0.83) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| Deoxysappanone B 7,3'-Dimethyl Ether Acetate SCHEMBL12998502 | 0.90 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29903813 | 0.90 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4731838 | 0.90 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16647710 | 0.90 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29903803 | 0.90 | CYP3A4 (1.00) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16264014 | 0.84 | CYP3A4 (0.72) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23882776 | 0.79 | CYP3A4 (0.65) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30251254 | 0.79 | CYP3A4 (0.65) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305068-A1 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305068-A1 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| WO-2008067451-A1 | NOVEL 3-BENZYLIDINE AND 3-BENZYL SUBSTITUTED CHROMANONES | ITHERX PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305068-A1 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | GOLT1B, NPC1L1, NPC1 | CYP3A4 4800/4885MAPT 459/4885MEN1 3909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.