SCHEMBL16264708

SCHEMBL16264708

CC(C)CC(C)(C)c1cnc[nH]1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 6/20 0.42
CYP17A1 P05093 6/20 0.40
CYP3A4 P08684 5/20 0.40
HRH3 Q9Y5N1 6/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 1/20 0.39
GLA P06280 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.39
NFKB1 P19838 1/20 0.39
THPO P40225 1/20 0.39
LMNA P02545 1/20 0.38
APEX1 P27695 1/20 0.38
BLM P54132 1/20 0.38
FKBP5 Q13451 1/20 0.35
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22694971 0.85 HRH4 (0.40) HRH4CYP17A1CYP3A4HRH3ALDH1A1
SCHEMBL14415970 0.76 HRH4 (0.44) HRH4HRH3ALDH1A1MEN1GLA
Hydrochloric Acid SCHEMBL25371613 0.74 HRH4 (0.43) HRH4HRH3ALDH1A1MEN1GLA
SCHEMBL14857108 0.74 HRH4 (0.43) HRH4CYP17A1CYP3A4HRH3ALDH1A1
SCHEMBL26052366 0.73 HRH1 (0.42) HRH4HRH3LMNAAPEX1
SCHEMBL26812529 0.73 HRH4 (0.42) HRH4CYP17A1CYP3A4HRH3ALDH1A1
SCHEMBL22082313 0.70 CPB1 (0.41) HRH4HRH3ALDH1A1MEN1GLA
SCHEMBL14857315 0.69 HRH3 (0.39) HRH4CYP17A1CYP3A4HRH3ALDH1A1
SCHEMBL20696520 0.69 HRH3 (0.44) HRH4CYP3A4HRH3CYP1A2
SCHEMBL27617871 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2741731-B1 ENCAPSULATES PROCTER & GAMBLE (US) 2017-05-17 EP disclosed
WO-2014189906-A2 ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2014-11-27 WO disclosed