SCHEMBL16265259

SCHEMBL16265259

C=CC(=O)Oc1ccc(/C(C)=C(\C)c2ccc(OC(=O)C=C)c(OC(=O)C=C)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.49
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
GAA P10253 2/20 0.45
KDM4E B2RXH2 2/20 0.45
RAB9A P51151 1/20 0.45
TDP1 Q9NUW8 2/20 0.40
KMT2A Q03164 3/20 0.38
TOP1 P11387 2/20 0.38
THRA P10827 1/20 0.36
ELANE P08246 2/20 0.36
MAPT P10636 2/20 0.36
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
HSD17B10 Q99714 2/20 0.35
MEN1 O00255 1/20 0.35
EGFR P00533 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15338895 0.94 TSHR (0.50) THRBALDH1A1TSHRGAAKDM4E
SCHEMBL15339113 0.90 TSHR (0.44) THRBALDH1A1TSHRGAAKDM4E
SCHEMBL15339159 0.88 KDM4E (0.41) THRBALDH1A1TSHRGAAKDM4E
SCHEMBL2583966 0.87 THRB (0.61) THRBALDH1A1KDM4ERAB9ATDP1
SCHEMBL16265261 0.86 THRB (0.46) THRBALDH1A1TSHRGAAKDM4E
SCHEMBL15339149 0.86 TSHR (0.41) THRBALDH1A1TSHRGAAKDM4E
SCHEMBL15338889 0.86 TSHR (0.41) THRBALDH1A1TSHRGAAKDM4E
SCHEMBL16265312 0.85 TSHR (0.43) THRBALDH1A1TSHRGAAKDM4E
SCHEMBL12604131 0.84 KMT2A (0.47) THRBALDH1A1TSHRGAAKDM4E
SCHEMBL17461516 0.84 KMT2A (0.47) THRBALDH1A1TSHRGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed