SCHEMBL16265459

SCHEMBL16265459

CCCCC(CC)CN1C(=O)C(Cl)=C(Cl)C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 5/20 0.38
TSHR P16473 3/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5335314 0.85 ALDH1A1 (0.40) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL13578757 0.83 ALDH1A1 (0.39) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL12502653 0.79 ALDH1A1 (0.46) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL19421857 0.79 ALDH1A1 (0.41) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL3106921 0.79 ALDH1A1 (0.44) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL13478140 0.79 ALDH1A1 (0.39) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL29783582 0.78 ALDH1A1 (0.45) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL14868159 0.78 CHRM2 (0.42) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL17622373 0.78 ALDH1A1 (0.40) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL9491373 0.78 ALDH1A1 (0.45) ALDH1A1KMT2AKDM4ETHRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014191358-A1 NOVEL COMPOUNDS WITH SEMICONDUCTING PROPERTIES SOLVAY SA (BE) 2014-12-04 WO disclosed
WO-2014191358-A1 NOVEL COMPOUNDS WITH SEMICONDUCTING PROPERTIES SOLVAY SA (BE) 2014-12-04 WO disclosed
EP-2808327-A1 Novel compounds with semiconducting properties Solvay SA (BE) 2014-12-03 EP disclosed
EP-2808327-A1 Novel compounds with semiconducting properties Solvay SA (BE) 2014-12-03 EP disclosed