Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16265740 | 0.92 | CYP3A4 (0.36) | CYP3A4CYP2C19GAAPIK3CDMAPT | |
| SCHEMBL16265828 | 0.88 | CYP3A4 (0.39) | CYP3A4CYP2C19GAAPIK3CDMAPT | |
| SCHEMBL16265872 | 0.87 | PIK3CD (0.37) | GAAPIK3CDALDH1A1CHRM2ADRA2B | |
| SCHEMBL16265479 | 0.83 | CYP3A4 (0.35) | CYP3A4CYP2C19GAAALDH1A1KDM4E | |
| SCHEMBL16265608 | 0.83 | CYP3A4 (0.43) | CYP3A4CYP2C19GAAPIK3CDMAPT | |
| SCHEMBL16265792 | 0.82 | CYP3A4 (0.39) | CYP3A4CYP2C19GAAPIK3CDMAPT | |
| SCHEMBL16265695 | 0.79 | CYP3A4 (0.38) | CYP3A4CYP2C19GAAMAPTALDH1A1 | |
| SCHEMBL16265615 | 0.79 | CYP3A4 (0.38) | CYP3A4CYP2C19GAAPIK3CDMAPT | |
| SCHEMBL16265754 | 0.78 | POLB (0.32) | PIK3CDCYP2D6 | |
| SCHEMBL16265543 | 0.78 | CYP3A4 (0.40) | CYP3A4CYP2C19GAAPIK3CDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2808329-B1 | Silyl-Protected Nitrogen-Containing Cyclic Compounds and their method of preparation | SHINETSU CHEMICAL CO (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-9233988-B2 | Silyl-protected nitrogen-containing cyclic compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| CN-104211725-A | Silyl-protected nitrogen-containing cyclic compounds and making method | SHINETSU CHEMICAL CO | 2014-12-17 | — | — | CN | disclosed |
| US-20140357862-A1 | SILYL-PROTECTED NITROGEN-CONTAINING CYCLIC COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-12-04 | — | — | US | disclosed |
| EP-2808329-A1 | Silyl-Protected Nitrogen-Containing Cyclic Compounds and Making Method | Shin-Etsu Chemical Co., Ltd. (JP) | 2014-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357862-A1 | SILYL-PROTECTED NITROGEN-CONTAINING CYCLIC COMPOUNDS AND MAKING METHOD | PRMT9, CCNO, IPO9 | CYP3A4 2494/4885CYP2C19 1911/4885GAA 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.