Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155244 | 0.93 | ESR1 (0.58) | ESR1ESR2ALOX5MAPTACHE | |
| SCHEMBL23269791 | 0.91 | ESR1 (0.55) | ESR1ESR2ALOX5MAPTACHE | |
| SCHEMBL990339 | 0.90 | ESR1 (0.63) | ESR1ESR2ALOX5MAPTACHE | |
| SCHEMBL30394271 | 0.90 | ESR1 (0.63) | ESR1ESR2ALOX5MAPTACHE | |
| SCHEMBL1157982 | 0.88 | ESR1 (0.50) | ESR1ESR2ALOX5CYP1A2CYP2C19 | |
| Anthracene SCHEMBL8502505 | 0.87 | ESR1 (0.61) | ESR1ESR2ALOX5MAPTACHE | |
| SCHEMBL19810099 | 0.87 | ESR1 (0.61) | ESR1ESR2ALOX5MAPTACHE | |
| SCHEMBL28808096 | 0.86 | ESR1 (0.60) | ESR1ESR2ALOX5MAPTACHE | |
| SCHEMBL2804923 | 0.86 | ALOX5 (0.57) | ESR1ESR2ALOX5ALDH1A1HSD17B10 | |
| SCHEMBL5066070 | 0.85 | ESR1 (0.64) | ESR1ESR2ALOX5MAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067857-B2 | Fluorine-containing aromatic compound and manufacturing method therefor | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-06-30 | — | — | US | disclosed |
| US-20140357906-A1 | FLUORINE-CONTAINING AROMATIC COMPOUND AND MANUFACTURING METHOD THEREFOR | AGC Inc. (JP) | 2014-12-04 | — | — | US | disclosed |
| CN-104114522-A | Fluorine-containing aromatic compound and manufacturing method therefor | ASAHI GLASS CO LTD | 2014-10-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357906-A1 | FLUORINE-CONTAINING AROMATIC COMPOUND AND MANUFACTURING METHOD THEREFOR | AFF1, AFF2, AFF4 | ESR1 2838/4885ESR2 1960/4885ALOX5 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.