Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24019599 | 0.89 | HPGD (1.00) | TSHRHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL24019574 | 0.88 | HPGD (0.80) | TSHRHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL24209657 | 0.85 | MAPT (0.82) | TSHRHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL24019576 | 0.85 | HPGD (0.74) | TSHRHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL24210198 | 0.83 | KDM4E (0.64) | TSHRHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL24019594 | 0.82 | TP53 (0.72) | TSHRHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL24019575 | 0.81 | ALDH1A1 (1.00) | TSHRHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL24209749 | 0.81 | KMT2A (0.82) | TSHRALDH1A1MEN1KMT2AATM | |
| SCHEMBL21951986 | 0.78 | MAPT (0.71) | TSHRHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL24209699 | 0.78 | HPGD (0.79) | HPGDALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014191822-A1 | BENZOIC ACID DERIVATIVES AS IL-15Rα RECEPTOR INHIBITORS | WARSZAWSKI UNIWERSYTET MEDYCZNY (PL) | 2014-12-04 | — | — | WO | disclosed |