Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 15/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 15/20 | 0.55 |
| ▸ | ITGAL | P20701 | 15/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756057 | 0.89 | ITGB2 (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL19158403 | 0.89 | ITGB2 (0.54) | ITGB2ICAM1ITGALMAPTPOLB | |
| SCHEMBL16270942 | 0.89 | ITGB2 (0.50) | ITGB2ICAM1ITGALALDH1A1HPGD | |
| SCHEMBL22296813 | 0.89 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL13813582 | 0.89 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL16270927 | 0.83 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL23992593 | 0.82 | ITGB2 (0.64) | ITGB2ICAM1ITGAL | |
| SCHEMBL4756084 | 0.82 | ITGB2 (0.67) | ITGB2ICAM1ITGAL | |
| SCHEMBL4755948 | 0.81 | ITGB2 (0.66) | ITGB2ICAM1ITGAL | |
| SCHEMBL17992523 | 0.81 | ITGB2 (0.66) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881823-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EYE DISORDERS | SARCODE BIOSCIENCE INC (US) | 2014-12-03 | — | — | EP | disclosed |