Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 16/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 16/20 | 0.54 |
| ▸ | ITGAL | P20701 | 16/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157704 | 0.91 | ITGB2 (0.51) | ITGB2ICAM1ITGALALDH1A1HPGD | |
| SCHEMBL25912568 | 0.90 | ITGB2 (0.43) | ITGB2ICAM1ITGAL | |
| SCHEMBL16270926 | 0.89 | ITGB2 (0.55) | ITGB2ICAM1ITGALMAPTPOLB | |
| SCHEMBL4756057 | 0.88 | ITGB2 (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL13813582 | 0.88 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL22296813 | 0.88 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL4756084 | 0.82 | ITGB2 (0.67) | ITGB2ICAM1ITGAL | |
| SCHEMBL23992593 | 0.81 | ITGB2 (0.64) | ITGB2ICAM1ITGAL | |
| SCHEMBL25912527 | 0.81 | ITGB2 (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL12169796 | 0.81 | ITGB2 (0.65) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3195861-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DRY EYE DISORDERS | SARcode Bioscience Inc. (US) | 2017-07-26 | — | — | EP | disclosed |