SCHEMBL1627170

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1622884	0.93	ITK (0.50)	NPC1RAB9ALMNACYP1A2SMN1; SMN2
	SCHEMBL2903568	0.85	ITK (0.43)	NPC1RAB9ALMNASMN1; SMN2ITK
	SCHEMBL13869803	0.81	ITK (0.60)	NPC1RAB9ASMN1; SMN2ITKLCK
	SCHEMBL2898022	0.80	ITK (0.47)	NPC1RAB9ALMNASMN1; SMN2ITK
	SCHEMBL27645976	0.78	ITK (0.54)	ITKLCKTXKSYKMAPK1
	SCHEMBL14508645	0.78	CYP1A2 (0.47)	NPC1RAB9ALMNACYP1A2SMN1; SMN2
	SCHEMBL1620556	0.77	ITK (0.51)	RAB9ASMN1; SMN2ITKLCKTXK
	SCHEMBL1623118	0.77	ITK (0.51)	NPC1RAB9ASMN1; SMN2ITKLCK
	SCHEMBL1623956	0.76	ITK (0.58)	ITKLCKTXKSYK
	SCHEMBL1623119	0.76	ITK (0.47)	NPC1RAB9ACYP1A2SMN1; SMN2ITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.