SCHEMBL16273694

SCHEMBL16273694

Cc1cc(O)cc(F)c1OCc1ccccc1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
MAPT P10636 4/20 0.34
MEN1 O00255 3/20 0.34
ALDH1A1 P00352 3/20 0.34
GAA P10253 3/20 0.34
KMT2A Q03164 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
THRB P10828 2/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 2/20 0.34
THRA P10827 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAOB P27338 5/20 0.34
PARP10 Q53GL7 3/20 0.34
PARP15 Q460N3 2/20 0.34
PARP14 Q460N5 2/20 0.34
BLM P54132 2/20 0.34
ALOX12 P18054 1/20 0.34
PLEC Q15149 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17616616 0.87 FFAR1 (0.36) FFAR1FFAR4MAPTL3MBTL1THRB
SCHEMBL16273704 0.81 FFAR1 (0.34) FFAR1FFAR4MAPTMEN1ALDH1A1
SCHEMBL16273661 0.80 TP53 (0.47) FFAR1FFAR4ALDH1A1THRBTHRA
SCHEMBL17616647 0.78 TSHR (0.34) FFAR1FFAR4MAPTALDH1A1THRB
SCHEMBL16273630 0.78 MAOB (0.49) MAPTMEN1ALDH1A1KMT2ATHRB
SCHEMBL16273624 0.77 CYP3A4 (0.36) FFAR1FFAR4MAPTMEN1ALDH1A1
SCHEMBL16273712 0.76 MRGPRX4 (0.40) FFAR1FFAR4MAPTMEN1ALDH1A1
SCHEMBL21317985 0.75 FFAR1 (0.34) FFAR1FFAR4MAPTMEN1ALDH1A1
SCHEMBL16273692 0.75 FFAR4 (0.43) FFAR1FFAR4SLC6A2SLC6A4
SCHEMBL17616636 0.74 MCL1 (0.42) FFAR1FFAR4MAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 US disclosed
EP-3029030-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR Sumitomo Chemical Company, Limited (JP) 2016-06-08 EP disclosed
EP-3006440-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME Sumitomo Chemical Company Limited (JP) 2016-04-13 EP disclosed
WO-2015016373-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR 住友化学株式会社 (JP) 2015-02-05 WO disclosed
WO-2014192953-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME 住友化学株式会社 (JP) 2014-12-04 WO disclosed