SCHEMBL16273692

SCHEMBL16273692

Cc1cc(O)ccc1OCc1ccccc1N

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.43
FFAR1 O14842 3/20 0.43
CD274 Q9NZQ7 6/20 0.40
MRGPRX4 Q96LA9 2/20 0.40
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
ESR2 Q92731 1/20 0.38
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17616639 0.86 L3MBTL1 (0.49) FFAR4FFAR1MRGPRX4SLC6A4
SCHEMBL18831472 0.85 CDK4 (0.48) FFAR4FFAR1CD274MRGPRX4RECQL
SCHEMBL16273701 0.83 PTGDR2 (0.39) FFAR4FFAR1CD274
SCHEMBL20425118 0.83 MEN1 (0.45) FFAR4FFAR1SLC6A4
SCHEMBL16273699 0.83 KMT2A (0.40) SLC6A2SLC6A4SLC6A3RECQL
SCHEMBL17616634 0.82 ALDH1A1 (0.39) FFAR4FFAR1CD274SLC6A4
SCHEMBL7599662 0.82 CDK4 (0.46)
SCHEMBL18831608 0.81 MRGPRX4 (0.39) FFAR4FFAR1CD274MRGPRX4
SCHEMBL16273696 0.81 MRGPRX4 (0.49) FFAR4MRGPRX4
SCHEMBL16273709 0.81 F2 (0.40) FFAR4CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029030-B1 TETRAZOLINONE COMPOUND, AND USE THEREFOR SUMITOMO CHEMICAL CO (JP) 2019-09-04 EP disclosed
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 US disclosed
EP-3029030-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR Sumitomo Chemical Company, Limited (JP) 2016-06-08 EP disclosed
EP-3006440-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME Sumitomo Chemical Company Limited (JP) 2016-04-13 EP disclosed
WO-2015016373-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR 住友化学株式会社 (JP) 2015-02-05 WO disclosed
WO-2014192953-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME 住友化学株式会社 (JP) 2014-12-04 WO disclosed