Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274226 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNASMN1; SMN2EPHX1 | |
| SCHEMBL16274228 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL16274230 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL4305747 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL4305748 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL15250703 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL11455157 | 0.79 | NPC1 (0.52) | ALDH1A1MAPTLMNAEPHX1GAA | |
| SCHEMBL11455158 | 0.79 | NPC1 (0.52) | ALDH1A1MAPTLMNAEPHX1GAA | |
| SCHEMBL31339240 | 0.78 | SMN1; SMN2 (0.62) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL3890914 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNASMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014192841-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ISOXAZOLINE COMPOUND | 住友化学株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |