Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274700 | 0.87 | PDE4B (0.48) | KDM4EALDH1A1GAATSHRMAPK1 | |
| SCHEMBL16274683 | 0.87 | ALDH1A1 (0.44) | KDM4EALDH1A1GAATSHRMAPK1 | |
| SCHEMBL16274845 | 0.86 | RPS6KB1 (0.39) | ALDH1A1TSHRMAPK1HSD17B10LMNA | |
| SCHEMBL16274665 | 0.86 | KDM4E (0.48) | KDM4ERECQLALDH1A1GAATSHR | |
| SCHEMBL1522959 | 0.85 | KDM4E (0.53) | KDM4ERECQLALDH1A1GAATSHR | |
| SCHEMBL16274812 | 0.85 | MAPT (0.46) | KDM4EALDH1A1GAATSHRMAPK1 | |
| SCHEMBL16274809 | 0.85 | CYP1A2 (0.42) | KDM4EALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL3516982 | 0.85 | KDM4E (0.47) | KDM4ERECQLALDH1A1GAATSHR | |
| SCHEMBL3514749 | 0.84 | KDM4E (0.47) | KDM4ERECQLALDH1A1GAATSHR | |
| SCHEMBL3517692 | 0.84 | KDM4E (0.47) | KDM4ERECQLALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810944-A1 | HETEROCYCLIC COMPOUND HAVING ANTI-HIV ACTIVITY | Toyama Chemical Co., Ltd. (JP) | 2014-12-10 | — | — | EP | disclosed |