Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16276139 | 0.85 | LMNA (0.67) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL9052488 | 0.85 | LMNA (0.67) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL16276140 | 0.85 | LMNA (0.67) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL16276146 | 0.85 | LMNA (0.67) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL16276089 | 0.84 | LMNA (0.62) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL3456997 | 0.82 | LMNA (0.69) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL8900671 | 0.81 | LMNA (0.62) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL16276041 | 0.81 | LMNA (0.65) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL3455804 | 0.81 | LMNA (0.65) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 | |
| SCHEMBL16276044 | 0.81 | LMNA (0.65) | LMNASMN1; SMN2TSHRL3MBTL1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014192865-A1 | PHENYLPIPERAZINE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |