SCHEMBL162763

SCHEMBL162763

O=C(O)C=C(Cc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.63
CYP3A4 P08684 1/20 0.63
CES1 P23141 2/20 0.52
CES2 O00748 1/20 0.52
AKR1B1 P15121 1/20 0.52
CTBP2 P56545 1/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
TSHR P16473 3/20 0.45
KDM4E B2RXH2 1/20 0.45
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
EPHX2 P34913 1/20 0.42
PAM P19021 2/20 0.41
ABCC4 O15439 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162762 1.00 CYP2C9 (0.63) CYP2C9CYP3A4CES1CES2AKR1B1
SCHEMBL165767 1.00 CYP2C9 (0.63) CYP2C9CYP3A4CES1CES2AKR1B1
SCHEMBL30772424 0.88 CYP2C9 (0.55) CYP2C9CYP3A4CES1CES2AKR1B1
Di(Hydroxyethyl)Ether SCHEMBL10732320 0.87 CYP3A4 (0.50) CYP2C9CYP3A4CES1CES2AKR1B1
SCHEMBL9363950 0.84 CYP3A4 (0.59) CYP2C9CYP3A4CES1CES2AKR1B1
SCHEMBL9363945 0.84 CYP3A4 (0.59) CYP2C9CYP3A4CES1CES2AKR1B1
SCHEMBL27637055 0.84 CYP3A4 (0.50) CYP2C9CYP3A4CES1CES2AKR1B1
SCHEMBL1585419 0.83 CYP3A4 (0.46) CYP2C9CYP3A4CES1CES2AKR1B1
SCHEMBL6222325 0.83 CYP3A4 (0.46) CYP2C9CYP3A4CES1CES2AKR1B1
SCHEMBL30745648 0.82 CYP3A4 (0.58) CYP2C9CYP3A4CES1CES2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2145921-B1 Vulcanizable polymer compositions ARLANXEO DEUTSCHLAND GMBH (DE) 2017-01-25 EP claimed
EP-2199326-B1 Vulcanizable polymer compositions LANXESS DEUTSCHLAND GMBH (DE) 2014-10-29 EP claimed
EP-0598091-B2 FUNCTIONALIZED POLYMER NANOPARTICLES, METHOD OF PREPARATION AND USE THEREOF PROLABO SA (FR) 2003-08-13 EP claimed
EP-0802236-B1 CURABLE POLYMETHYLSILSESQUIOXANE COMPOSITION DOW CORNING ASIA LTD (JP) 2002-04-10 EP claimed
EP-0598091-B1 FUNCTIONALIZED POLYMER NANOPARTICLES, METHOD OF PREPARATION AND USE THEREOF PROLABO SA (FR) 1997-09-24 EP claimed
JP-7072664-A None JP disclosed
CN-114144458-B Stabilizer composition for silyl modified polymeric sealants 科莱恩国际有限公司 2023-11-10 CN disclosed
EP-4263202-A1 METHOD FOR PREPARING A POLYURETHANE POLYMER Bostik SA (FR) 2023-10-25 EP disclosed
CN-116917396-A Stabilizer composition for silyl modified polymer sealants 科莱恩国际有限公司 2023-10-20 CN disclosed
EP-4198100-A1 HEAT-CURABLE ADHESIVE COMPOSITION FORMING A TEMPERATURE-STABLE ADHESIVE JOINT Bostik SA (FR) 2023-06-21 EP disclosed
EP-4185652-A1 ADHESIVE COMPOSITION FOR MAKING WATERPROOF BREATHABLE ARTICLES Bostik SA (FR) 2023-05-31 EP disclosed
WO-2022129810-A1 METHOD FOR PREPARING A POLYURETHANE POLYMER BOSTIK SA (FR) 2022-06-23 WO disclosed
US-4414128-A SURFACTANT, A TERPENE, OXY SOLVENT THE PROCTER & GAMBLE COMPANY (US) 1983-11-08 US disclosed
US-4397943-A POLYMERIC 1,2,4-TRIAZOLO-1,5-A-PYRIMIDINES AS STABILIZERS FUJI PHOTO FILM CO., LTD. (JP) 1983-08-09 US disclosed
EP-0063017-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-20 EP disclosed
US-4347168-A ANIONIC, ALKOXYLATED NONIONIC AND QUATERNARY AMMONIUM CATIONIC SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1982-08-31 US disclosed
EP-0040882-A1 Liquid detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1981-12-02 EP disclosed
US-4240450-A HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS L'OREAL (FR) 1980-12-23 US disclosed
EP-0002084-A1 Granular detergent compositions for improved greasy soil removal THE PROCTER & GAMBLE COMPANY (US) 1979-05-30 EP disclosed
EP-0001310-A1 Low phosphate detergent composition for fabric washing THE PROCTER & GAMBLE COMPANY (US) 1979-04-04 EP disclosed