Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162763 | 1.00 | CYP2C9 (0.63) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| SCHEMBL162762 | 1.00 | CYP2C9 (0.63) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| SCHEMBL30772424 | 0.88 | CYP2C9 (0.55) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| Di(Hydroxyethyl)Ether SCHEMBL10732320 | 0.87 | CYP3A4 (0.50) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| SCHEMBL9363950 | 0.84 | CYP3A4 (0.59) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| SCHEMBL9363945 | 0.84 | CYP3A4 (0.59) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| SCHEMBL27637055 | 0.84 | CYP3A4 (0.50) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| SCHEMBL1585419 | 0.83 | CYP3A4 (0.46) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| SCHEMBL6222325 | 0.83 | CYP3A4 (0.46) | CYP2C9CYP3A4CES1CES2AKR1B1 | |
| SCHEMBL30745648 | 0.82 | CYP3A4 (0.58) | CYP2C9CYP3A4CES1CES2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145921-B1 | Vulcanizable polymer compositions | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-01-25 | — | — | EP | claimed |
| EP-2199326-B1 | Vulcanizable polymer compositions | LANXESS DEUTSCHLAND GMBH (DE) | 2014-10-29 | — | — | EP | claimed |
| EP-3728355-B1 | NITRILE DIENE CARBOXYLIC ACID ESTER COPOLYMERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2022-04-20 | — | — | EP | disclosed |
| EP-3668922-B1 | VULCANISABLE COMPOSITIONS CONTAINING HYDROGENATED NITRILE RUBBER, VULCANIZATES PREPARED FROM SAME AND THEIR USE | ARLANXEO DEUTSCHLAND GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |
| US-11248077-B2 | Polymerizable composition for optical material and molded product | MITSUI CHEMICALS, INC. (JP) | 2022-02-15 | — | — | US | disclosed |
| EP-3720885-B1 | METHOD FOR PRODUCING NITRILE RUBBERS WITH RUTHENIUM COMPLEX CATALYSTS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2021-12-01 | — | — | EP | disclosed |
| EP-3684604-B1 | VULCANIZABLE HNBR COMPOSITION WITH HIGH THERMAL CONDUCTIVITY | ARLANXEO DEUTSCHLAND GMBH (DE) | 2021-11-24 | — | — | EP | disclosed |
| US-20210054126-A1 | POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL AND MOLDED PRODUCT | MITSUI CHEMICALS, INC. (JP) | 2021-02-25 | — | — | US | disclosed |
| EP-3728355-A1 | NITRILE-DIENE-CARBOXYLIC ACID ESTER COPOLYMERS | ARLANXEO Deutschland GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3728452-A1 | VULCANIZED HNBR PRODUCT WITH IMPROVED HOT AIR RESISTANCE | ARLANXEO Deutschland GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3720885-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS USING RUTHENIUM COMPLEX CATALYSTS | ARLANXEO Deutschland GmbH (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-2267037-A1 | Use of wholly or partially hydrated nitrile rubbers | LANXESS Deutschland GmbH (DE) | 2010-12-29 | — | — | EP | disclosed |
| CN-101458341-B | Combination for stopping uv optical lens and capable of preventing aetiolation in heat treatment process and optical lens using same | SHIN DAE SPECIALTIES CO LTD | 2010-12-15 | — | — | CN | disclosed |
| CN-101458341-A | Combination for stopping uv optical lens and capable of preventing aetiolation in heat treatment process and optical lens using same | SHIN DAE SPECIALTIES CO LTD (KR) | 2009-06-17 | — | — | CN | disclosed |
| US-6551814-B1 | Functional, cell-free pyruvate formate lyase obtained from a toluene-degrading bacterium and a functional, cell-free pyruvate formate lyase activating enzyme of a toluene-degrading bacterium | OHIO UNIVERSITY | 2003-04-22 | — | — | US | disclosed |
| US-6541656-B2 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY, LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| US-6395539-B1 | A DNA CAPABLE OF EXPRESSING A TOLUENE DEGRADING ENZYME; FOR THE DEGRADATION OF COMPOUNDS CONTAINED IN A LIQUID OR SOLID WASTE STREAM | OHIO UNIVERSITY | 2002-05-28 | — | — | US | disclosed |
| US-20010034300-A1 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY LTD. (JP) | 2001-10-25 | — | — | US | disclosed |
| WO-2000072650-A2 | COMPOSITIONS AND METHODS FOR BIOREMEDIATION | OHIO UNIVERSITY (US) | 2000-12-07 | — | — | WO | disclosed |
| WO-1998050587-A1 | COMPOSITIONS AND METHODS FOR BIOREMEDIATION | OHIO UNIVERSITY (US) | 1998-11-12 | — | — | WO | disclosed |