Ensulizole

Ensulizole

SCHEMBL16277

O=S(=O)(O)c1ccc2[nH]c(-c3ccccc3)nc2c1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.79
NPBWR1 P48145 2/20 0.58
SCD O00767 1/20 0.56
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
GAA P10253 2/20 0.54
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 3/20 0.52
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 3/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 7/20 0.48
TP53 P04637 3/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ensulizole SCHEMBL29405567 1.00 HDAC6 (0.79) HDAC6NPBWR1SCDNPC1RAB9A
Ensulizole SCHEMBL4619449 1.00 HDAC6 (0.79) HDAC6NPBWR1SCDNPC1RAB9A
Ensulizole SCHEMBL2142368 0.99 HDAC6 (0.77) HDAC6NPBWR1SCDNPC1RAB9A
Ensulizole SCHEMBL1276069 0.99 HDAC6 (0.77) HDAC6NPBWR1SCDNPC1RAB9A
Ensulizole SCHEMBL17351653 0.99 HDAC6 (0.77) HDAC6NPBWR1SCDNPC1RAB9A
Ensulizole SCHEMBL3173650 0.99 HDAC6 (0.77) HDAC6NPBWR1SCDNPC1RAB9A
Ensulizole SCHEMBL22187023 0.97 HDAC6 (0.75) HDAC6NPBWR1SCDNPC1RAB9A
Ensulizole SCHEMBL27885503 0.97 HDAC6 (0.75) HDAC6NPBWR1SCDNPC1RAB9A
Ensulizole SCHEMBL1072602 0.93 HDAC6 (0.70) HDAC6NPBWR1SCDNPC1RAB9A
SCHEMBL318730 0.92 HDAC6 (0.67) HDAC6NPBWR1SCDCHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27279 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075332-A Composition, preparation method thereof and sun-screening composition 2026-05-26 CN claimed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
WO-2026099270-A1 BIODEGRADABLE UV ABSORBERS AND USES THEREOF II BASF SE (DE) 2026-05-15 WO claimed
WO-2026099732-A1 COSMETIC PRODUCTS WITH SOLAR PROTECTION COMPRISING POROUS POWDERS COATED WITH LIPOPHILIC AGENTS WITH SPF BOOSTER EFFECT INTERCOS S.P.A. (IT) 2026-05-15 WO claimed
WO-2026098831-A1 USE OF A PERSONAL CARE COMPOSITION FOR IMPROVING THE BARRIER FUNCTION OF SKIN UNILEVER IP HOLDINGS B.V. (NL) 2026-05-15 WO claimed
CN-122031293-A Efficient waterproof and sun-proof synergistic composition suitable for oil-in-water type and application thereof 诺斯贝尔化妆品股份有限公司 2026-05-15 CN claimed
CN-122031322-A Plant composition for resisting photo-thermal injury and realizing anti-inflammatory repair and application thereof 青漾时光(武汉)生物科技有限公司 2026-05-15 CN claimed
US-20260130837-A1 SPF BOOSTER AND SUNCARE FORMULATIONS INCLUDING SAME DOW SILICONES CORP (US) 2026-05-14 US claimed
CN-121566056-B Sulfonic modified ZIF-67 coated diaphragm and preparation method and application thereof 浙江理工大学 2026-05-12 CN claimed
US-20260125827-A1 POLYHYDROXYALKANOATE-BASED FIBERS DANIMER IPCO LLC (US) 2026-05-07 US claimed
US-4686099-A Aerosol waterproof sunscreen compositions CHESEBROUGH-POND'S INC. 1987-08-11 US claimed
US-4683134-A HIGH VISCOSITY, GELS, ETHYL CELLULOSE, CROSSLINKED POLYACRYLIC ACID PALINCZAR VICTOR 1987-07-28 US claimed
US-4671956-A STABILITY; SIDE EFFECT REDUCTION L'OREAL (FR) 1987-06-09 US claimed
US-4671955-A ETHYL HYDROXYETHYL CELLULOSE AND AN ULTRAVIOLET RADIATION ABSORBER PALINCZAR VICTOR 1987-06-09 US claimed
EP-0216084-A2 Improved sunscreen and moisturizer Richardson-Vicks, Inc. (US) 1987-04-01 EP claimed
EP-0207287-A2 Indole derivatives, process for their preparation and cosmetic preparation containing them BAYER AG (DE) 1987-01-07 EP claimed
US-4603046-A TRI(HYDROXYALKYL)RUTOSIDE, HUMECTANTS CHARLES OF THE RITZ GROUP LTD. (US) 1986-07-29 US claimed
US-4284621-A SUNSCREEN FOR SKIN BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US claimed
EP-0005182-B1 COMPOSITION AGAINST THE ACTION OF LIGHT BAYER AG (DE) 1981-07-29 EP claimed
EP-0005182-A1 Composition against the action of light BAYER AG (DE) 1979-11-14 EP claimed