⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815449 | 0.77 | — | — | |
| SCHEMBL1397085 | 0.73 | — | — | |
| SCHEMBL814307 | 0.73 | — | — | |
| SCHEMBL2820291 | 0.71 | THRB (0.35) | — | |
| SCHEMBL20912532 | 0.68 | — | — | |
| Methyl Alcohol SCHEMBL28241707 | 0.68 | THRB (0.32) | — | |
| SCHEMBL15967421 | 0.67 | — | — | |
| SCHEMBL9621604 | 0.65 | — | — | |
| SCHEMBL1705608 | 0.64 | — | — | |
| SCHEMBL28253431 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10241234-B2 | Silicone hydrogel soft contact lens having wettable surface | HOYA CORPORATION (JP) | 2019-03-26 | — | — | US | disclosed |
| EP-2840431-B1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORP (JP) | 2016-09-07 | — | — | EP | disclosed |
| EP-2840431-A1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORPORATION (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-20140362339-A1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORPORATION (JP) | 2014-12-11 | — | — | US | disclosed |