Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16280694 | 0.87 | DPP4 (1.00) | DPP4 | |
| SCHEMBL12687222 | 0.84 | DPP4 (1.00) | DPP4 | |
| SCHEMBL16280705 | 0.80 | DPP4 (1.00) | DPP4 | |
| SCHEMBL555121 | 0.74 | DPP4 (0.79) | DPP4 | |
| SCHEMBL2019018 | 0.74 | DPP4 (0.69) | DPP4 | |
| SCHEMBL2019020 | 0.74 | DPP4 (0.69) | DPP4 | |
| SCHEMBL13820049 | 0.72 | DPP4 (0.78) | DPP4 | |
| SCHEMBL16280699 | 0.71 | DPP4 (1.00) | DPP4KCNH2 | |
| SCHEMBL4668769 | 0.71 | ALDH1A1 (0.59) | DPP4 | |
| SCHEMBL12687228 | 0.71 | DPP4 (1.00) | DPP4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2680851-B1 | FUSED BICYCLIC HETEROCYCLES USEFUL AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | MERCK SHARP & DOHME (US) | 2016-08-17 | — | — | EP | disclosed |
| US-8907086-B2 | Fused bicyclic heterocycles useful as dipeptidyl peptidase-IV inhibitors | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8907086-B2 | Fused bicyclic heterocycles useful as dipeptidyl peptidase-IV inhibitors | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |