⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309378 | 1.00 | — | — | |
| SCHEMBL5311447 | 0.85 | TRPV1 (0.41) | — | |
| SCHEMBL5307039 | 0.83 | TRPV1 (0.44) | — | |
| SCHEMBL5306407 | 0.81 | TRPV1 (0.48) | — | |
| SCHEMBL14753958 | 0.81 | — | — | |
| SCHEMBL4208579 | 0.81 | — | — | |
| SCHEMBL24074517 | 0.79 | — | — | |
| SCHEMBL14753869 | 0.79 | — | — | |
| SCHEMBL28839196 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL17695269 | 0.79 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569324-B9 | AMINOGLYCOSIDE DERIVATIVES | REMPEX PHARMACEUTICALS INC (US) | 2018-03-28 | — | — | EP | disclosed |
| EP-2569324-B1 | AMINOGLYCOSIDE DERIVATIVES | REMPEX PHARMACEUTICALS INC (US) | 2017-12-06 | — | — | EP | disclosed |
| US-8906868-B2 | Aminoglycoside derivatives | REMPEX PHARMACEUTICALS, INC. (US) | 2014-12-09 | — | — | US | disclosed |