Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781897 | 1.00 | TSHR (0.36) | TSHRPTPN1KISS1RALDH1A1MMP1 | |
| SCHEMBL1784217 | 0.95 | TSHR (0.33) | TSHRPTPN1 | |
| SCHEMBL1782009 | 0.81 | TSHR (0.42) | TSHRALDH1A1TDP1 | |
| SCHEMBL14661746 | 0.80 | OR51E2 (0.42) | TSHRALDH1A1 | |
| SCHEMBL1782638 | 0.80 | ALDH1A1 (0.40) | KISS1RALDH1A1TDP1 | |
| SCHEMBL14662148 | 0.80 | OR51E2 (0.42) | TSHRALDH1A1 | |
| SCHEMBL8495464 | 0.80 | OR51E2 (0.42) | TSHRALDH1A1 | |
| SCHEMBL2945494 | 0.80 | OR51E2 (0.42) | TSHRALDH1A1 | |
| SCHEMBL14661330 | 0.80 | OR51E2 (0.42) | TSHRALDH1A1 | |
| SCHEMBL14661739 | 0.80 | OR51E2 (0.42) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906868-B2 | Aminoglycoside derivatives | REMPEX PHARMACEUTICALS, INC. (US) | 2014-12-09 | — | — | US | disclosed |